110) Zhu H, Xue X, Wang E, Wallack M, Na H, Hooker JM, Kowall N, Tao Q, Stein TD, Wolozin B, Qiu WQ. Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease. Neuropharmacology. 2017

109) Hooker JM, Strebl MG, Schroeder FA, Wey HY, Ambardekar AV, McKinsey TA, Schoenberger M. Imaging cardiac SCN51 using the novel F-18 radiotracer radiocaine. Scientific Reports. 2017

108) Atzil S, Touroutoglou A, Rudy T, Salcedo S, Feldman R, Hooker JM, Dickerson BC, Catana C, Feldman Barrett L. Dopamine in the medial amygdala network mediates human bonding. PNAS. 2017

107) Hu K, Patnaik D, Collier TL, Lee KN, Gao H, Swoyer MR, Rotstein BH, Krishnan HS, Liang SH, Wang J, Yan Z, Hooker JM, Vasdev N, Haggarty SJ, Ngai MJ. Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging. ACS Medicinal Chemistry Letters. 2017.

106) Schuetze KB, Stratton MS, Blakeslee WW, Wempe MF, Wagner FF, Holson EB, Kuo YM, Andrews AJ, Gilbert TM, Hooker JM, McKinsey TA. Overlapping and Divergent Actions of Structurally Distinct HDAC Inhibitors in Cardiac Fibroblasts. JPET. 2017

105) Fuin N, Pedemonte S, Catalano OA, Izquierdo-Garcia D, Soricelli A, Salvatore M, Heberlein K, Hooker JM, Van Leemput K, Catana C. PET/MR Imaging in the Presence of Metal Implants: Completion of the Attenuation Map from PET Emission Data. J Nucl Med. 2017

104) Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM.  Nasal neuron PET imaging quantifies neuron generation and degeneration. The Journal of Clinical Investigation. 2017

103) Schroeder FA, Gilbert TG, Feng N, Taillon B, Volkow N, Innis R, Hooker JM, Lipska B. Expression of HDAC2 but not HDAC1 Transcript is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia. ACS Chemical Neuroscience. 2016. 

102) Keliher E, Ye Y, Wojtkiewicz G, Aguirre A, Tricot B, Senders M, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen J, Swirski F, Wey HY, Hooker JM, Fayad Z, Mulder W, Weissleder R, Nahrendorf M. Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischemic heart disease. Nature Communications. 2017

101) *Wang C, Schroeder FA, Hooker JM. Development of New Positron Emission Tomography Radiotracer for BET Imaging. ACS Chemical Neuroscience. 2016

100) Campbell MG, Mercier J, Genicot C, Vouverneur V, Hooker JM, Ritter T. Bridging the Gaps in 18F PET Tracer Development. Nature Chemistry. 2017

99) Herranz E, Giannì C, Louapre C, Treaba CA, Govindarajan ST, Ouellette R, Loggia ML, Sloane JA, Madigan N, Izquierdo-Garcia D, Ward N, Mangeat G, Granberg T, Klawiter EC, Catana C, Hooker JM, Taylor N, Ionete C, Kinkel RP, Mainero C. The neuroinflammatory component of gray matter pathology in multiple sclerosis. Ann. Neurol. 2016

98) Ricq EL, Hooker JM, Haggarty SJ. Activity-Dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch. Journal of Biological Chemistry. 2016

97) Alshikho MH, Zurcher NR, Loggia ML, Cernasov P, Chonde DB, Izquierdo Garcia D, Yasek JE, Catana C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N. Glial Activation Co-localizes with Structural Abnormalities in Amyotrophic Lateral Sclerosis. Neurology. 2016

96) Kumar V, Boucher Y, Liu H, Ferreira D, Hooker J, Catana C, Hoover AJ, Ritter T, Jain RK, Guimaraes AR. Noninvasive assessment of losartan-induced increase in functionalmicrovasculature and drug delivery in ancreatic ductal adenocarcinoma. Translational Oncology. 2016

95) Wey HY, Gilbert TM, Zurcher NR, She A, Bhanot A, Tailon BD, Schroeder FA, Haggarty SJ, Hooker JM. Insights into neuroepigenetics through human histone deacetylase PET imaging. Science Translational Medicine. 2016.

94) Ricq EL, Hooker JM, Haggarty SJ. Toward Development of Epigenetic Drugs for CNS Disorders: Modulating Neuroplasticity via H3K4 Methylation. Psychiatry and Clinical Neurosciences. 2016

93) Rotstein BH, Placzek MS, Krishnan HS, Pekosak A, Collier TL, Wang C, Liang SH, Burstein ES, Hooker JM, Vasdev N. Preclinical PET neuroimaging of Preclinical PET neuroimaging of [11C]bexarotene. Molecular Imaging. 2016

92)  Mandeville JB, Sander CYM, Wey HY, Hooker JM, Hansen HD, Svarer C, Knudsen GM, Rosen BR. A regularized full reference tissue model for PET neuroreceptor mapping. Neuroimage. 2016

91) Neumann CN, Hooker JM, *Ritter T. Concerted nucleophilic aromatic substitution with 19F− and 18F−. Nature. 2016

90) Heidari P, Szretter AK, Rushford LE, Stevens M, Collier L, Sore J, Hooker JM, Mahmood U. Design, construction and testing of a low-cost automated 68Gallium-labeling synthesis unit for clinical use. AJNMMI. 2016

89) Rotstein BH, Liang SH, Placzek MS, Hooker JM, Gee AD, Dolle F, Wilson AA, Vasdev N. 11C-C=O Bonds Made Easily for Positron Emission Tomography Radiopharmaceuticals. Chem. Soc. Rev. 2016

88) *Roffman JL, Tanner AS, Rodriquez-Thompson T, Silverstein NJ, Ho NF, Nitenson AZ, Chonde DB, Abi-Dargham A, Buckner RL, Manoach DS, Rosen BR, Hooker JM, Catana C. Dopamine D1 Signaling Organizes Network Dynamics Underlying Working Memory. Science Advances. 2016

87) *Albrecht DS, Granziera C, Hooker JM, Loggia ML. In vivo imaging of human neuroinflammation. ACS Chemical Neuroscience. 2016

86) Hoover AJ, Lazari M, Ren H, Narayanam MK, Murphey JM, van Dam RM, Hooker JM, *Ritter T. A Transmetalation Reaction Enables the Synthesis of [18F]5FU- Fluorouracil from [18F]Fluoride for Human PET Imaging. Organometallics. 2016

85) *Wang C, Placzek MS, Van de Bittner GC, Schroeder FA, Hooker JM. A Novel Radiotracer for Imaging Monoacylglycerol Lipase in the Brain Using Positron Emission Tomography. ACS Chemical Neuroscience. 2015

84) Strebl M, Wang C, Schroeder FA, Placzek MS, Wey HY, Van de Bittner GC, Neelamegam R, *Hooker JM. Development of a Fluorinated Class-I HDAC Radiotracer Reveals Key Chemical Determinants of Brain Penetrance. ACS Chemical Neuroscience. 2015

83) Wagner F, Lundh M, Taner K, McCarren P, Zhang YL, Chattopadhyay S, Gale J, Galbo T, Fisher S, Meier B, Vetere A, Richardson S, Morgan N, Christensen D, Gilbert T, Hooker JM, Leroy M, Walpita D, Mandrup-Poulsen T, Wagner B, Holson E. An isochemogenic set of inhibitors to define the therapeutic potential of HDACs in beta-cell protection.  ACS Chemical Biology. 2015

82) Lee SJ, Fowler JS, Alexoff D, Scheuller M, Kim D, Nauth A, Weber C, Kim SW, Hooker JM, Ma L, *Qu W. An efficient and practical synthesis of [2-11C]indole via superfast nucleophilic [11C]cyanation and RANEY® Nickel catalyzed reductive cyclization. Organic & Biomolecular Chemistry. 2015

81) Placzek MS, Zhao W, Wey HS, Morin TM, *Hooker JM. PET neurochemical imaging modes. Seminars in Nuclear Medicine. 2015.

80) *Sander CY, Hooker JM, Catana C, Rosen BR, Mandeville JB. Imaging agonist-induced D2/D3 receptor desensitization in vivo with PET/fMRI. Neuropsychopharmacology. 2015.

79) Wang H, Liu L, Yang L, Pan P, Hooker JM, Fowler JS, *Tonge PJ. Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase. Bioorg Med Chem Lett. 2015.

78) Placzek MS, Van de Bittner GC, Wey HS, Lukas SE, *Hooker JM. Immediate and persistent effects of salvinorin A on the kappa opioid receptor in rodents, monitored in vivo with PET. Neuropsychopharmacology. 2015.

77) Liang SH, Holland JP, Stephenson N, Kassenbrock A, Rotstein BH, Daignault CP, Lewis R, Collier TL, Hooker JM, *Vasdev N. PET neuroimaging studies of [18F]CABS13 in a double transgenic mouse model of Alzheimer’s disease and nonhuman primates. ACS Chemical Neuroscience. 2015.

76) *Wey HY, Wang C, Schroeder FA, Logan J, Price J, *Hooker JM. Kinetic Analysis and Quantification of [11C]Martinostat for in vivo HDAC Imaging of the Brain. ACS Chemical Neuroscience. 2015.

75) *Giancardo L, Sanchez-Ferro A, Butterworth I, Sanchez-Mendoza C, Hooker JM. Psychomotor Impairment Detection via Finger Interactions with a Computer Keyboard During Natural Typing. Scientific Reports. 2015 accepted.

74) Huang X, Liu W, Hooker JM, *Groves JT. Targeted Fluorination with the Fluoride Ion by Manganese-Catalyzed Decarboxylation. Angewandte Chemie International Edition. 2015.

73) Borra RJH, Cho HS, Bowen S, Attenberger U, Arabasz G, Catana C, Josephson L, Rosen B, Guimaraes AR, *Hooker JM. Quantitative PET Measurements in Simultaneous PET/MR Whole-Body Imaging: A Pilot Study in a Baboon Model. EJNMMI Physics. 2015.

72) Zurcher NR, Bhanot A, McDougle CJ, *Hooker JM. A systematic review of molecular imaging (PET and SPECT) in autism spectrum disorder: current state and future research opportunities. Neuroscience & Biobehavioral Reviews. 2015.

71) Lee HG, Milner P, Placzek M, *Buchwald S, *Hooker, JM. Virtually Instantaneous, Room-temperature [11C]-Cyanation Using Biaryl Phosphine Pd(0) Complexes. J Am Chem Soc. 2015.

70) Zurcher NR, Loggia ML, Lawson R, Chonde DB, Izquierdo-Garcia D, Yasek JE, Akeju O, Catana C, Rosen BR, Cudkowicz ME, *Hooker JM, *Atassi N. Increased in vivo Glial Activation in Patients with Amyotrophic Lateral Sclerosis: assessed with [11C]-PBR28. NeuroImage: Clinical. 2015. 

69) *Akeju O, Loggia ML, Catana C, Pavone KJ, Vazquez R, Rhee J, Ramirez VC, Chonde DB, Izquierdo-Garcia D, Arabasz G, Hsu S, Habeeb K, Hooker JM, Napadow V, Brown EN, Purdon. Thalamic Functional Connectivity to the Default Mode Network is a Fundamental Neural Correlate of Consciousness. eLife. 2015

68) *Loggia ML, Chonde DB, Akeju O, Arabaz G, Catana C, Edwards RR, Hill E, Hsu S, Izquierdo-Garcia D, Ji R, Riley M, Wasan AD, Zurcher NR, Albrecht DS, Vangel MG, Rosen BR, Napadow V, Hooker JM.  Evidence of brain glial activation in chronic pain patients.  Brain. 2015

67) *McDougle CJ, Landino SM, Vahabzadeh A, O'Rourke J, Zurcher NR, Finger BC, Palumbo ML, Helt J, Mullett JE, Hooker JM, Carlezon WA. Toward an Immune-Mediated Subtype of Autism Spectrum Disorder. Brain Research. 2014

66) Van de Bittner G, Ricq EL, *Hooker JM. A Philsophy for CNS Radiotracer Design. Accounts of Chemical Research. 2014. 

65) Wang C, Schroeder FA, Wey HY, Borra R, Wagner FF, Reis SA, Kim SW, Holson EB, Haggarty SJ, *Hooker JM. In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs. J. Med. Chem. 2014. 

64) Wang H, Lu Y, Liu L, Kim SW, Hooker JM, Fowler JS, *Tonge PJ. Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus. Eur. J. Med Chem. 2014

63) Schroeder FA, Wang C, Van de Bittner GC, Neelamegam R, Takakura WR, Karunakaran P, Wey HY, Reis SA, Gale J, Zhang YL, Holson EB, Haggarty SJ, *Hooker JM. PET imaging demonstrates HDAC target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat. ACS Chemical Neuroscience. 2014. 

62) *Wey HY, Catana C, Hooker JM, Dougherty DD, Knudsen GM, Wang DJ, Chonde DB, Rosen BR, Gollub RL, Kong J. Simultaneous fMRI-PET of the Opioidergic Pain System in Human Brain. NeuroImage. 2014.

61) Rotstein B, Wey HY, Shoup T, Wilson AA, Liang SH, *Hooker JM, *Vasdev N. PET Imaging of Fatty Acid Amide Hydrolase with [18F]DOPP in Non-Human Primates. Molecular Pharmaceutics. 2014

60) Villien M, Wey HY, Mandeville JB, Catana C, Polimeni JR, Sander CY, Zürcher NR, Chonde DB, Fowler JS, Rosen BR, *Hooker JM. Dynamic Functional Imaging of Brain Glucose Utilization using fPET-FDG. NeuroImage. 2014.

59) Ren H, Wey HY, Strebl M, Neelamegam R, *Ritter TR, *Hooker, JM. Synthesis and Imaging Validation of [18F]MDL100907 Enabled by Ni-Mediated Fluorination. ACS Chemical Neuroscience. 2014

58) Granda ML, Schroeder FA, Borra RHJ, Schauer N, Aisaborhale E, Guimaraes AR, *Hooker JM. First D1-like receptor PET imaging of the rat and primate kidney: implications for human disease monitoring. American Journal of Physiology, Renal Physiology. 2014 

57) Seo YJ, Kang Y, Muench L, Reid A, Caesar S, Logan J , Fevier-Wagner F, Holson EB, Haggarty SJ, Weiss P, King P, Carter P, Volkow ND, Fowler JS, *Hooker JM, *Kim SW. Image-guided synthesis reveals potent blood-brain barrier permeable histone deacetylase inhibitors.  ACS Chemical Neuroscience. 2014 

56) Diyabalanage HVK, Van de Bittner GC, Ricq EL, *Hooker JM. A chemical strategy for the cell-based detection of HDAC activity. ACS Chemical Biology. 2014 

55) Huang X, Liu W, Ren H, Neelamegam R, *Hooker JM, *Groves JT. Late Stage Benzylic C-H Fluorination with [18F]Fluoride for PET Imaging. Journal of the American Chemical Society. 2014 

54) Rotstein BH, Hooker JM, Woo J, Collier TL, Brady TJ, *Liang SH, *Vasdev N. Synthesis of [11C]Bexarotene by Cu-Mediated [11C]Carbon Dioxide Fixation and Preliminary PET Imaging. ACS Med Chem Lett. 2014 

53) Neelamegam R, Hellenbrand T, Schroeder FA, Wang CW, *Hooker JM. Imaging evaluation of 5HT2C agonists, [11C]WAY-163909 and [11C]vabicaserin, formed by Pictet-Spengler cyclization. J Med Chem. 2014

52) Wang C, Eessalu TE, Barth VN, Mitch CH, Wagner FF, Hong Y, Neelamegam R, Schroeder FA, Holson EB, Haggarty SJ, *Hooker JM. Design, Synthesis, and Evaluation of Hydroxamic Acid-Based Molecular Probes for In Vivo Imaging of Histone Deacetylase (HDAC) In Brain. American Journal of Nuclear Medicine and Molecular Imaging. 2014

51) Seo YJ, Muench L, Reid A, Chen J, Kang Y, Hooker JM, Volkow ND, Fowler JS, *Kim SW. Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain. Bioorg. Med Chem Lett. 2013

50) Wang C, Schroeder FA, *Hooker JM. Visualizing epigenetics: current advances and advantages in HDAC PET imaging techniques. Neuroscience. 2013

49) Wang C, Wilson CM, Moseley CK, Carlin SM, Hsu S, Arabasz G, Schroeder FA, Sander CY, *Hooker JM. Evaluation of potential PET imaging probes for the orexin 2 receptors. Nuclear Medicine and Biology. 2013

48) Schroeder FA, Lewis MC, Fass DM, Wagner FF, Zhang YL, Hennig KM, Gale J, Zhao WN, Reis S, Barker DD, Berry-Scott E, Kim SW, Clore EL, Hooker JM, Holson EB, Haggarty SJ, *Petryshen TL. A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests.  PlosOne. 2013

47) *Kim SW, *Hooker JM, Otto N, Win K, Muench L, Shea C, Carter P, King P, Reid AE, Volkow ND, Fowler JS. Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. Nuclear Medicine and Biology. 2013

46) Schroeder FA, Chonde DB, Riley MM, Moseley CK, Granda ML, Wilson CM, Wagner FF, Zhang YL, Gale J, Holson EB, Haggarty SJ, *Hooker JM. FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors. Neuroscience Letters. 2013

45) Wang Y, Zhang YL, Henning K, Gale JP, Hong Y, Cha A, Riley M, Wagner F, Haggarty SJ, Holson E, *Hooker JM. Class I HDAC imaging using [3H]CI-994 autoradiography. Epigenetics. 2013 

44) Sander CY, Hooker JM, Catana C, Normindin MD, Alpert NM, Knudsen GM, Vanduffel W, Rosen BR, *Mandeville JB. Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI. PNAS. 2013

43)  Rotstein B, Liang SH, Holland J, Collier L, Hooker J, Wilson AA, *Vasdev N. 11CO2 Fixation: A Renaissance in PET Radiochemistry. Chem Comm. 2013

42) Wang C, Moseley CK, Carlin SM, Wilson CM, Neelamegam R, *Hooker JM.  Radiosynthesis and Evaluation of [11C]EMPA as a potential PET Tracer for Orexin 2 Receptors.  Bioorg Med Chem Lett. 2013

41) *Mandeville JB, Sander CY, Jenkins BG, Hooker JM, Catana C, Vanduffel W, Alpert NM, Rosen BR, Normandin MD. A receptor-based model for dopamine-induced fMRI signal. Neuroimage. 2013 

40) Kamlet AS, Neumann C, Lee E, Carlin SM, Moseley CK, Stephenson N, *Hooker JM, *Ritter TR. Application of Palladium-mediated 18F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation. PlosOne. 2013

39) Ho NF, Hooker JM, Sahay A, Holt DJ, Roffman JL. In vivo imaging of adult human hippocampal neurogenesis: progress, pitfalls and promise. Molecular Psychiatry. 2013

38) Granda ML, Carlin SM, Moseley CK, Neelamegam R, Mandeville JB, *Hooker JM. Synthesis and evaluation of methylated arylazepine compounds for PET imaging of 5-HT2c receptors. ACS Chemical Neuroscience. 2012.

37) Moseley CK, Carlin SM, Neelamegam R, *Hooker JM. An Efficient and Practical Radiosynthesis of [(11)C]Temozolomide. Org Lett. 2012 

36) Lee E, Hooker JM, Ritter T. Nickel-Mediated Oxidative Fluorination for PET with Aqueous [(18)F] Fluoride. J Am Chem Soc. 2012 Oct 24;134(42):17456-8.

35) Diyabalanage HV, Granda ML, *Hooker JM. Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer. Cancer Lett. 2012 

34) Weinstein EA, Liu L, Ordonez AA, Wang H, Hooker JM, Tonge PJ, Jain SK. Noninvasive Determination of 2-[18F]-Fluoroisonicotinicacid hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis Infected Mice. Antimicrob Agents Chemother. 2012 

33) Neelamegam R, Ricq EL, Malvaez M, Patnaik D, Norton S, Carlin SM, Hill IT, Wood MA, Haggarty SJ, *Hooker JM. Brain-penetrant LSD1 inhibitors can block memory consolidation. ACS Chemical Neuroscience. 3 (2): 120–128 (2012).

32) Riss PJ, Hooker JM, Shea C, Xu Y, Carter P, Warner D, Ferrari V, Kim SW, Aigbirhio FI, Fowler JS, Roesch F. Characterisation of [11C]PR04.MZ in papio anubis baboon: A selective high-affinity radioligand for quantitative imaging of the dopamine transporter. Bioorg Med Chem Lett. 22 (1): 679-682 (2012).

31) Lee E, Kamlet AS, Powers DC, Neumann CN, Boursalian GB, Furuya T, Choi DC, *Hooker JM, *Ritter T. A Fluoride-derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging.  Science. 334 (6056): 639-642 (2011).

30) Behrens CR, Hooker JM, Obermeyer AC, Romanini DW, Katz EM, Francis MB. Rapid Chemoselective Bioconjugation through Oxidative Coupling of Anilines and Aminophenols. Journal of the American Chemical Society. 133 (41): 16398–16401 (2011).

29) Reid AE, Kim SW, Seiner B, Fowler FW, Hooker J, Ferrieri R, Babst B and Fowler JS.  Radiosynthesis of C-11 labeled auxin (3-indolyl[1-11C]acetic acid) and its derivatives from gramine. Journal of Labelled Compounds and Radiopharmaceuticals. 54 (10): 678-680 (2011).

28) Ran C, Zhang Z, Hooker J, Moore A. In Vivo Photoactivation Without "Light": Use of Cherenkov Radiation to Overcome the Penetration Limit of Light. Mol Imaging Biol. 14 (2): 156-162 (2012).

27) *Hooker JM, Kim SW, Reibel AT, Alexoff D, Xu Y, Shea C. Evaluation of [11C]metergoline as a PET radiotracer for 5HTR in nonhuman primates. Bioorg Med Chem. 18 (22): 7739-7745 (2010).

26) Schonberger M, Leggett C, Kim SW, *Hooker JM. Synthesis of [11C]SSR149415 and preliminary imaging studies using positron emission tomography. Bioorg Med Chem Lett. 20 (10): 3103-6 (2010).

25) Liu L, Xu Y, Shea C, Fowler JS, *Hooker JM, *Tonge PJ. Radiosynthesis and bioimaging of the tuberculosis chemotherapeutics isoniazid, rifampicin and pyrazinamide in baboons. J Med Chem. 53(7): 2882-91 (2010).

24) Biegon A, Won Kim S, Logan J, Hooker JM, Muench L, Fowler JS. Nicotine Blocks Brain Estrogen Synthase (Aromatase): In Vivo Positron Emission Tomography Studies in Female Baboons. Biol Psychiatry. 67(8): 774-7 (2010).

23) *Hooker JM. Modular strategies for PET imaging agents. Curr Opin Chem Biol. 14(1): 105-11 (2010) PMCID: 2819636.

22) *Hooker JM, Kim SW, Alexoff D, Xu Y, Shea C, Reid A, et al. Histone Deacetylase Inhibitor MS-275 Exhibits Poor Brain Penetration: Pharmacokinetic Studies of [11C]MS-275 using Positron Emission Tomography. ACS Chemical Neuroscience. 1(1): 65-73 (2009).

21) *Hooker JM, Munro TA, Beguin C, Alexoff D, Shea C, Xu Y, et al. Salvinorin A and derivatives: protection from metabolism does not prolong short-term, whole-brain residence. Neuropharmacology. 57(4): 386-91 (2009).

20) Riss PJ, Hooker JM, Alexoff D, Kim SW, Fowler JS, Rösch F. [11C]PR04MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient 11C-O-methylation and initial small animal PET studies.  Bioorg. Med. Chem. Lett. 19(15): 4343-4345 (2009).

19) *Hooker JM, Reibel AT, Hill SM, Schueller MJ, Fowler JS. One-pot, Direct Incorporation of [11C]-CO2 into Carbamates. Angewandte Chemie International Edition. 48(19): 3482-3485 (2009).

18) Schiffer WK, Liebling CNB, Reiszel C, Hooker JM, Brodie JD, Dewey SL.  Cue-induced dopamine release predicts preference:  PET studies in freely moving rodents. The Journal of Neuroscience. 29(19): 6176-6185 (2009).

17) Reid AE, Hooker JM, Shumay EM, Kim SW, Logan J, Shea C, Xu Y, Volkov ND, Fowler JS. Assessment of [18F]FAHA for PET imaging of HDAC in the baboon brain. Nuclear Medicine and Biology  39(3): 247-258 (2009).

16) Fowler JS, Volkow ND, Logan J, Alexoff D, Telang F, Wang GJ, Hooker JM, Wong C, Hubbard B, Carter P, Warner D, King P, Shea C, Xu Y, Muench L, Pujari N, Apelskog K. Modafinil Blocks Dopamine Transporters and Decreases Dopamine D2 Receptor Availability in Human Brain: Evidence of Dopaminergic Effects. Journal of the American Medical Association.  301(11): 1148-1154 (2009). Highlighted in (among others) the NY Times and The New Yorker.

15) Kim SW, Biegon A, Katsamanis ZE, Ehrlich C, Hooker JM, Shea C, Muench L, Xu Y, King P, Carter P, Alexoff DL, Fowler JS. Reinvestigation of the Synthesis and Evaluation of [N-methyl-11C]Vorozole, a Radiotracer Targeting Cytochrome P450 Aromatase.  Nuclear Medicine and Biology 36(3): 323-334 (2009).

14) *Hooker JM, Patel V, Kothari S, *Schiffer WK.  Metabolic Changes in the Rodent Brain after Acute Administration of Salvinorin A. Molecular Imaging and Biology. 11(3): 137-143 (2009).

13) *Hooker JM, Schönberger M, Schieferstein H, Fowler JS.  A simple, rapid method for the preparation of [11C]-formaldehyde. Angewandte Chemie International Edition. 47(32): 5989-5992 (2008).  Highlighted in: C&E News Concentrate, CancerResearchJournal.com, Society of Nuclear Medicine Editor’s Choice, Nature Chemistry

12) *Hooker JM, Xu Y, Carter P, Schiffer W, Shea C, Fowler JS.  Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset, short duration of effects in humans.  NeuroImage. 41(3), 1044-50 (2008). Highlighted in:  PBS News Hour & many online news articles

 

------- Publications in the Francis Group at UC Berkeley --------

11) Hooker JM, O’Neil JP, Romanini DW, Taylor SE, Francis MB. Genome-free Viral Capsids as Carriers for Positron Emission Tomography Radiolabels.  Molecular Imaging and Biology. 10: 182-191 (2008).

10) Datta A, Hooker JM, Botta M, Francis MB, Raymond K.  Relaxometric Properties of Gadolinium Hydroxypyridonate – Viral Capsid Conjugates:  Nano-sized Contrast Media with High Relaxivities at High Field.  Journal of the American Chemical Society.  130 (8): 2546-2552, (2008).

9) Hooker JM, Datta A, Botta M, Raymond K, Francis MB.  Magnetic Resonance Contrast Agents from Viral Capsid Shells: A Comparison of Exterior and Interior Cargo Strategies Nano Letters. 7 (8): 2207 -2210 (2007).

8) Kovacs EW, Hooker JM, Romanini DW, Holder PG, Berry KE, Francis MB. Dual-Surface Modified Bacteriophage MS2 as an Ideal Scaffold for a Viral Capsid-Based Drug Delivery System.  Bioconjugate Chemistry. 18 (4): 1140 -1147 (2007). (Cover).

7) Johnson HR, Hooker JM, Francis MB, Clark DS. Solubilization and Stabilization of Bacteriophage MS2 in Organic Solvents.  Biotechnology and Bioengineering. 97 (2): 224 (2007).

6) Hooker JM, Esser-Kahn AP, Francis MB.  Modification of Aniline Containing Proteins Using an Oxidative Coupling Strategy. Journal of the American Chemical Society. 128: 15558–15559 (2006).

5) Hooker JM, Kovacs, EW & Francis, MB. Interior surface modification of bacteriophage MS2. Journal of the American Chemical Society. 126: 3718-3719 (2004). Highlighted in: C&E News, Faculty of 1000 Biology

 

------- Publications in the College of Textiles at North Carolina State University -------

4) Hooker JM, Hinks, D, Montero G, Icherenska M. Enzyme-Catalyzed Hydrolysis of Polyester Cyclic Trimer. J. Applied Polymer Science. 89: 2545-2552 (2003).

3) Hooker JM, Hinks D, Freeman HS. Synthesis, properties, and application of four new 1:2 aluminium complexed azo dyes. Coloration Technology. 119: 41-47 (2003).

2) Montero G, Hinks D, Hooker J. Reducing problems of cyclic trimer deposits in supercritical carbon dioxide polyester dyeing machinery. Journal of Supercritical Fluids. 26: 47-54 (2003).

1) Hooker J, Hinks D, Montero G, Conlee C. Synthesis of N,N-diethyl-N-{4-[(E)-(4-nitrophenyl)diazenyl]phenyl}amine via in situ diazotisation and coupling in supercritical carbon dioxide. Coloration Technology. 118: 273-276 (2002).